Save time - and hands!
This is the striking slogan that Indian company Glassco is using to promote its innovative 500.AG glass ceramic hotplate with magnetic stirrer at LABVOLUTION 2017. Its simple Click System also ensures that a damaged ceramic hotplate can be replaced in no time.

The glass ceramic hot plate is resistant to chemicals and mechanical stress caused by sharp objects, making it extremely scratch resistant. However, should the plate on the 500.AG get damaged, it can be very easily replaced – without having to buy a whole new device. Glassco has also made safety a top priority, integrating a unique "spill away" feature that protects users from overflowing liquids. After all, what lab worker hasn't at one time or another forgotten a solution on the hot plate and been left to clean messy equipment or - worse still - had to cool scalded fingers? The 500.AG has been designed to avoid precisely such incidents with an overflow system that prevents burns.

Other features of the 500.AG hotplate with magnetic stirrer include a digital temperature controller operated via an LED display, a pre-installed platinum temperature sensor that monitors the system when in use, and a display that warns when a surface temperature exceeds 50 degrees Celsius. An external temperature probe can also be added via a DIN connector. The device achieves a maximum stirring speed of 2,000 RPM and is designed to heat as much as five liters up to a maximum temperature of 550 degrees Celsius. The display shows both temperature and speed separately, and malfunctions are flagged up with an error code.
Glassco Laboratory Equipment Pvt. Ltd. (133004 Ambala Cantt, India), Hall 20, Stand C34
Contact: Mrs. Gurpreet Kaur
Tel.: +91 171 2891633

I've got two photos for you today!
CrysCam UV, which Dunn Labortechnik is exhibiting at LABVOLUTION, automatically scans 96-well plates and captures both a visual and UV image of all wells and sub-wells, so that they can be viewed simultaneously and compared for each well.

Based in Asbach, Germany, and celebrating 35 years in business, Dunn Labortechnik GmbH has made itself a name in the sector by offering skilled advice, dependable service, high-quality specialist products and rapid delivery. Among the numerous products the company is showcasing in Hannover is the CrysCam UV from Art Robbins Instruments, a digital microscope that automatically scans 96-well plates and captures a visual and UV image (334 nm and 365 nm) of all wells and sub-wells.

The key feature is that the visual and UV image for all wells can be simultaneously displayed and compared in parallel for each individual well. The CrysCam UV is designed to be ideal for protein crystallography, since droplets can even be captured on a nano scale. Particularly large crystals can be imaged using the "deep field slicing" function, which captures multiple images at different levels and merges them into a single high-resolution image. The camera of the CrysCam UV, an Artemis VS60, stays focused even when zooming and can view individual wells with or without polarizer. The resolution of the Artemis VS60 (2750 x 2250 pixels) supplies excellent digital pictures at 2.37 microns/pixel. The device is compatible with all SBS-format and Linbro plates and is equipped with an integrated cooling function to set temperatures down to as low as -10 °C and an enclosure that blocks any stray light.
Dunn Labortechnik GmbH (53567 Asbach, Germany), Hall 20, Stand A59
Contact: Hannelore Dunn
Tel.: +49 2683 43094

Green is the new red...
StainIN Green from start-up HiQu is set to replace the infamous and potentially mutagenic red dye ethidium bromide - which should see nucleic acids in labs everywhere changing hue from the usual red to a fresh green.

Besides enjoying a vivid new color, scientists can also look forward to lower health risks (as shown in an Ames test for carcinogenicity). StainIN Green is just as easy to work with as ethidium bromide and, according to its makers HiQu, is also four times more sensitive. StainIn Green performs well against other - green - rivals, being twice as productive and also detecting the presence of barely more than 0.1 ng DNA in both agarose and polyacrylamide gels. What’s more, because StainIN Green can be used for tagging directly in the gel, it eliminates the need to dye the gel after the run and remove the dye in another step.

StainIN Green binds with both double- and single-strand DNA, tagging it with a green fluorescence. RNA is also bound by the dye, a unique property of the dye being that this is tagged with a red fluorescence that can be detected using UV light, blue light or even the same filters used for the green fluorescence. As the dye is harmless to users and also does less damage to tagged DNA, its developers say this makes it ideal for detecting DNA that is destined for subsequent cloning. And if, despite all that, some scientists still want the DNA in their gel to be red, HiQu has a solution - StainIN Red. This red fluorescent dye with a detection limit of > 0.3 ng DNA is still twice as sensitive as ethidium bromide, and produces bands that can be detected as usual under UV light with the same filters, but without the dreaded risk of mutagenic activity.
hiQu GmbH (76703 Kraichtal, Germany), Hall 20, Stand A12 (4)
Contact: Rasa Sehlmeyer
Tel.: +49 7250 33 13 401

The pipetting robot to kick-start your automation drive?
At LABVOLUTION 2017, BRAND is demonstrating how its new Liquid Handling Station’s price-performance ratio and simple operation provide a cost-effective automated solution for even small and medium-sized samples.

BRAND GmbH & Co. KG boasts one of the biggest cleanroom facilities in the sector worldwide, with around 6,000 m2 of production space and 3,200 m2 of certified cleanroom. Now, this market leader in measuring and metering equipment and high-quality life science consumables is exhibiting an impressive array of product innovations in Hannover. One of the main highlights is its new Liquid Handling Station, which combines 45 years of experience in liquid handling and more than 30 years of manufacturing high-quality disposable items.

The Liquid Handling Station is designed to suit all laboratories that require a compact and versatile workstation and are looking to close the gap between electronic pipettes and highly complex, expensive pipetting robots. Thanks to its compact design and innovative, patent-pending front door, the Liquid Handling Station has a footprint of just 595 x 485 millimeters and is 690/530 millimeters high with its door opened/closed. This makes it an ideal fit where space is limited or for installation under a safety hood.

The Liquid Handling Station has been developed for applications such as preparing assay-ready microtiter plates, PCR, qPCR and ELISA set-ups, serial dilutions and combinatorial biochemistry and uses exchangeable pipetting modules (liquid ends). The liquid ends can be changed quickly and easily with no need for tools. Liquid ends are available in three single-channel (1-50 µl, 10-200 µl, 40-1000 µl) and two 8-channel (1-50 µl, 20-300 µl) sizes. The volume testing of the pipette modules is performed according to ISO 8655 part 6. Seven freely configurable ANSI/SLAS-format work positions accommodate all kinds of disposable vessels, from individual up to 384-well plates, with an additional position for the waste box. The Liquid Handling Station’s intuitive software (also patent-pending) has been developed to help users set up simple, routine and complex pipetting tasks that follow standard laboratory procedures in a matter of minutes, even without prior programming experience.
BRAND GmbH & Co. KG (97877 Wertheim, Germany), Hall 20, Stand B33
Contact: Dr. Gerhard Ramaker
Mobil: +49 151 629 206 20

Backside illumination lights the way forward!
Photometrics is promoting the Prime 95B Scientific CMOS at LABVOLUTION 2017 as the first ever camera with 95-percent quantum efficiency. The camera utilizes backside illumination technology to maximize light collection.

Photometrics is proud to announce that its award-winning technology inside the Prime 95B Scientific CMOS camera enables efficient signal conversion for low-light imaging and localization-based super-resolution microscopy. The high-performance computing capacity means that images can be produced from very low light intensity, which protects preparations during life-science imaging and boosts the signal-to-noise ratio three- to five-fold.

"PrimeLocate" is the name Photometrics has coined for its camera's ability to actively select relevant fields in the preparation and only record this specific data. This key feature spares users the kind of unstoppable deluge of data that is all too often associated with high-resolution microscopy. The Prime 95B camera uses the full microscope field-of-view to capture 16-bit images at 41 frames per second (fps) or 12-bit images at 82fps and transmits these via a USB 3.0 interface. The combination of extreme sensitivity, low noise and high frame rates makes the Prime 95B eminently suited for applications such as confocal imaging, single molecule fluorescence and super-resolution microscopy (STORM, PALM.)
Photometrics (Arizona 85706, USA), Hall 20, Stand A06/1
Contact: Cyndy Nawrocki
Tel.: +1 520 547 2745

Fraunhofer has its eye on every little move!
The Fraunhofer Institute for Manufacturing Engineering and Automation - IPA is showcasing smart laboratory automation solutions at LABVOLUTION 2017, including a new tracking system that uses 3D image data processing to intelligently interpret hand movements and automatically record experiments.

To ensure laboratory processes can be reproduced and analyzed, technicians have to keep meticulous records of everything they do. However, manual records on paper or in electronic lab logs are very time-consuming to produce, are often incomplete and can be erroneous, too. Now researchers at the Fraunhofer IPA have developed a tracking system that uses 3D image processing to automatically record hand movements and intelligently evaluate them. At LABVOLUTION 2017, the team is demonstrating how the system helps save time, free up staff and produce better results.

As any researcher knows, every detail recorded in the write-up of an experiment can be crucial. Besides the most obvious information, such as the names and amounts of the substances used and temperatures, subconscious movements and habits can also influence results. The new tracking system from the Fraunhofer IPA is designed to make life easier for laboratory technicians by helping them keep everything in view. To achieve this, an intelligent 3D camera mounted on an enclosed workbench seamlessly records all hand movements and transmits data live to an information system. There, this data is evaluated using movement recognition algorithms, classified and recorded in a protocol. In this way, the system compiles a precise record of each separate step in the process, thus saving resources and freeing up staff to focus on the actual task in hand. As the tracking system only requires basic software and hardware, it can easily be installed in small laboratories, too.
Fraunhofer Institute for Manufacturing Engineering and Automation – IPA (70569 Stuttgart, Germany), Hall 20, Stand A45
Contact: Jörg-Dieter Walz
Tel.: +49 711 970-1667

Nobody does it better…
BMG LABTECH GmbH hails the new PHERAstar FSX it is showcasing at LABVOLUTION 2017 as the most sensitive HTS microplate reader on the market. The multi-mode microplate reader is designed to deliver maximum versatility and speed for all formats up to 3456-well microplates.

BMG LABTECH is one of the technological leaders in its specialist field of developing and manufacturing multi-mode microplate readers. The company has spent more than a quarter of a century developing innovative technologies tuned to the high-throughput screening needs of its customers in life sciences. The plate readers are all developed and manufactured at its headquarters in Ortenberg, including the PHERAstar FSX, which BMG LABTECH is rolling out at LABVOLUTION 2017 in Hannover as the new gold standard reader for high-throughput screening.

The PHERAstar FSX is based on the successful PHERAstar FS platform but has a series of unique new features aimed at raising it head and shoulders above all existing HTS readers. BMG LABTECH says its exceptional sensitivity and speed in reading fluorescence intensity (FI) and fluorescence polarization (FP) make the PHERAstar FSX the most sensitive plate reader on the market. Not only that, but the reader covers a much larger measuring range for luminescence, which achieves greater measuring precision and makes it more versatile. In response to screening facilities' never-ending quest to boost efficiency and cut costs by maximizing their throughput while simultaneously minimizing sample volumes, BMG LABTECH has acted as the driving force in recent years behind ongoing developments in Simultaneous Dual Emission (SDE) technology. This technology is crucial to both the PHERAstar FSX, and now also the AlphaPlex, in boosting the throughput enormously and halving measuring times.

The PHERAstar FSX owes its exceptional sensitivity to an innovative optical system consisting of three different light sources. It is equipped with the next generation of TRF/TR-FRET lasers for unbeatable performance in all kinds of assays. These deliver up to 60 light pulses per second, which not only boosts throughput but should also improve measuring accuracy for all plate formats.
BMG LABTECH GmbH (77799 Ortenberg, Germany), Hall 20, Stand B34
Contact: Lisa Schmid
Tel.: +49 781 96968-35

Crystal-clear design, ultra-pure water and a sparkling premiere!
ELGA, the global laboratory water brand from Veolia Water Technologies, is unveiling the PURELAB Chorus 1 Complete for producing type 1 ultra-pure water directly from tap water and the PURELAB Chorus 2+ for type II+ purified water at LABVOLUTION 2017. Two premieres worth toasting with a glass of something a bit bubblier…

ELGA is the global laboratory water brand of Veolia Water Technologies, a specialist in laboratory water preparation solutions for research and analysis, clinical diagnostics and health care for the past 80 years. ELGA systems are well known as a reliable and extremely cost-effective means of producing pure and ultra-pure water for all applications. What's more, they have received multiple awards for their convenient and intuitive operating systems. After all, their special modular concept offers laboratories the kind of versatile and space-saving options that leave room for later expansion.

Anyone who'd like to learn more about the right water quality for their own applications should pay a visit to Veolia Water Technologies Deutschland GmbH at the Lower Saxony Ministry of Science stand, where it is showcasing the new ELGA modular laboratory water systems. The stars of the show are the two new developments PURELAB Chorus 1 Complete and PURELAB Chorus 2+. The PURELAB Chorus 1 Complete is designed as an end-to-end solution for producing ultra-pure water directly from tap water, which is ideal for laboratories that require up to 100 liters of ultra-pure water (18.2 megohm cm) per day. Thanks to the straightforward, ergonomic and extremely user-friendly design of the PURELAB Chorus 1 Complete, water can be drawn either directly from the system or from an optional bolt-on halo dispenser. The distinguishing features of this new device are its full recirculation, integrated filtration and wide range of output options.

Its stablemate, the PURELAB Chorus 2+, is designed for higher bacterial and inorganic quality >15 megohm cm for sensitive analytical and life sciences applications that go beyond regular laboratory tasks. The PURELAB Chorus 2+ is available in two versions, which thanks to their full recirculation both guarantee consistent water purity - the PURELAB Chorus 2+ (RO/DI/UV) for purifying tap water into type II+ pure water for laboratories requiring up to 100 liters per day, and the PURELAB Chorus 2+ (RO/EDI/UV), which thanks to integrated EDI technology offers a cost-effective solution for laboratories that consume high volumes of water.
Veolia Water Technologies Deutschland GmbH (29227 Celle, Germany), Hall 19, Stand C80, co-exhibitor with Lower Saxony Ministry for Science
Contact: Nicole Rädisch
Tel.: +49 5141 803 205

Wanted! R+D service provider with own laboratory seeks…
Membrane, antibody, gel and electrophoresis system manufacturers, companies that handle minuscule volumes of liquid and users of service laboratories for bioanalytics should make a beeline for R+D service provider Hahn-Schickard's stand at LABVOLUTION - where the company is on the lookout for partners for its OpenWestern project.

Hahn-Schickard-Gesellschaft für angewandte Forschung e. V. uses microsystems engineering to develop intelligent products across all sectors - from the initial idea through to production. Within this broad remit, the R+D service provider focuses mainly on the growth areas of life sciences, medical technology, mobility and movement, Industry 4.0, sustainability, energy and the environment. It has developed fast, on-site lab-on-a-chip systems for diagnosing infectious diseases at its base in Freiburg, for example. Using a versatile pilot line for these CD-sized systems, Hahn-Schickard aims to offer its industrial customers more effective support in realizing their product visions from the initial idea to small-scale production. The company is now seeking project partners to help optimize time-consuming and laborious methods in Western Blot protein analysis.

The goal is to simplify, speed up and improve Western Blot for the process conditions of micro-fluidics by developing an automated system using open micro-fluidic structures and compatible biochemical protocols. Hahn-Schickard is currently looking for manufacturers of membranes, antibodies, gels and electrophoresis systems, companies that can handle minuscule volumes of liquid, and users (service laboratories for bioanalytics) as partners for the committee that will oversee the "Western Blots in open microfluidics" (OpenWestern) project. Their services are required to provide practical input for the project and inject valuable ideas. In return, they will enjoy direct access to the project's results. The project is scheduled to commence on 1 November this year and is likely to run until 31 May 2020. It is being funded by the AiF - Arbeitsgemeinschaft industrieller Forschungsvereinigungen "Otto von Guericke" e. V., and the University of Freiburg is the project partner of this interdisciplinary venture.
Hahn-Schickard-Gesellschaft für angewandte Forschung e. V. (79110 Freiburg, Germany), Hall 20, Stand E21, (E21/1),Topic: Baden-Württemberg Pavilion
Contact: Dipl.-Wirt.-Ing. (FH) Moritz Faller
Tel.: +49 7721 943-221

The new "must-have" for forward-looking laboratory operators
Certain products keep on popping up and pushing all the right buttons - you might call this the "iPhone effect". For automated liquid handlers, it’'s the new automated Biomek i Series Workstations, Biomek i5 and Biomek i7, that Beckman Coulter is now showcasing at LABVOLUTION 2017.

These two workstations from Beckman Coulter, one of the world's leading manufacturers of measuring instruments and test assays in the field of life sciences and clinical diagnostics, have been developed to optimize the reliability and self-sufficiency of laboratories working with medium and high sample throughputs. Numerous product innovations have been plowed into the development of these workstations to ensure users can always adapt their methods to changing workflow priorities.

At LABVOLUTION 2017, Beckman Coulter is demonstrating the numerous configuration options that the new series offers, which include individual and dual configurations of multi-channel (96/384) or Span-8 pipetting head models. Integrated data management and the autovalidation function in the Biomek software are designed to prevent programming errors and simplify complex sample and data processing. Beckman Coulter says this intelligent processing equips the Biomek i-Series with the most advanced pipetting techniques on the market.

The Biomek i-Series also stands out from the crowd with its spacious design and open deck, which provides access from all sides to allow the integration of additional devices mounted next to and outside the deck (analytical devices, external storage/incubation units, labware feeders, etc.). A 96-channel 1-ml pipetting head for large volumes speeds up the transfer of samples and facilitates more efficient mixing processes, while integrated cameras provide live footage and video recordings for e.g. system diagnoses. What’s more, users will welcome the slightly offset, rotating gripper designed to ensure optimum access to tightly packed decks and thus boost workflow efficiency. Last but not least, the device boasts an impressive illuminated status bar for enclosed devices that is visible from a distance and clearly indicates their current status with four different colors and patterns.
Beckman Coulter GmbH (47807 Krefeld, Germany), Hall 20, Stand C54
Contact: Uwe König
Tel.: +49 2151 333 647

EchoLUTION is DNA isolation at its best!
Startup BioEcho Life Sciences, which was founded in 2016 by a team of experienced molecular biologists, aims to revolutionize the isolation and cleanup of nucleic acids with the EchoLUTION technology it is showcasing at LABVOLUTION 2017 for the first time.

After years of working on the extraction of nucleic acids in various companies, the founders of BioEcho were only too aware of how little progress had been made in the speed, extraction rates and cleanup quality achieved with conventional methods. It was their belief that even the most firmly rooted techniques in molecular biology can still be improved that led them to found BioEcho, which saw the production line for EchoLUTION go into action last year.

EchoLUTION is the name of their innovative one-step DNA isolation technology. The manufacturers promise to make work protocols two- to five-times shorter while improving both extraction efficiency and the quality of the isolated nucleic acids. According to BioEcho, the EchoLUTION columns, which work on the principle of negative chromatography, are extremely efficient at absorbing contaminants, which achieves a high yield (more than 95 percent) of the DNA that needs isolating. If that’s not enough, BioEcho also points out that its products contain no harmful chemicals and produce significantly less plastic waste than their conventional counterparts - right down to the packaging! And all this innovative prowess comes without drastically increasing the price.

So far, EchoLUTION kits are available with columns for the cleanup of DNA from blood and cultivated cells, animal or human tissue, bacteria and plant tissue, while versions for isolating RNA and plasmid DNA are in the pipeline.
BioEcho Life Sciences GmbH (41542 Dormagen, Germany), Hall 20, Stand A12 (6)
Contact: Dr. Frank Schäfer
Mobile: +49 172 232 8806

A helping hand from lab-friendly Glomax
Remember the cute and kindly robot called "Baymax", who helps a young boy make his way in the Disney film Big Hero 6? Perhaps Glomax, the versatile detection device that Promega is promoting at LABVOLUTION 2017, is a close relative?

The upgraded version of Glomax, which now sports the suffix “Discover”, also likes to help out - with a broad range of applications in the laboratory. Glomax helps users to master the challenges of measuring luminescence, fluorescence, UV-visible absorption, BRET and FRET. The reader can work with plates ranging from 96 to 384 wells. And there are further parallels with its Disney relation to be found in the Glomax Discover maxim of “Set up, plug in and go!” Fortunately, the teething troubles suffered by Baymax are nowhere to be found in this detection device, which has been optimized specifically for Promega's wide range of assays. Glomax helps with the readout of reporter, kinetic and protein assays and with determining cell viability and apoptosis. Glomax works just as well as a stand-alone device or integrated into an automated high-throughput workflow.

To showcase the numerous potential applications, Promega is staging live demonstrations of various measuring tasks every day at its stand from 2 to 3 p.m. Visitors to LABVOLUTION 2017 are also being given an insight into the manufacturer's extensive portfolio of different assays for the analysis of cellular and biochemical processes. There will even be offers to rent a Glomax detection device for temporary use. Promega is keen to point out that the devices are constantly being developed to suit new applications, as they arise. You never know, maybe Disney might like to follow suit and finally release a Baymax 2, too?
Promega GmbH (68199 Mannheim, Germany), Hall 20, Stand B57
Contact: Christian Walczuch
Tel.: +49 621 8501-0

Tying technologies together
Under the slogan "Know your stuff 4.0", innoME GmbH is teaming up with its cooperation partner essentim at the Young and Innovative Companies Pavilion to reveal their simple and secure solution for measuring critical process parameters in gases and liquids.

innoME's core areas of expertise lie in developing and manufacturing sensor-based products for diagnostics & analytics, life sciences, medical technology and services. The fledgling company based in north-western Germany designs and produces evaluation systems, including disposable products, both for its customers and on its own initiative. To help detect different parameters, innoME integrates special sensors into products and custom-designs the measuring technology required for this purpose. The idea is that harmonizing the development and production of innovative sensor-based products under one roof dramatically cuts both development times and risks.

innoME and cooperation partner essentim are now appearing together at LABVOLUTION 2017 to showcase their simple and secure solution for measuring critical process parameters in gases and liquids. By combining innoME's printed biosensors and intelligent culture vessels with essentim's wireless sensor network and cloud solution, they believe they have come up with a process that is more flexible and simple than ever before. Thanks to the additional option of continuous optical monitoring using zenCell view and the ability to connect wirelessly to other devices in the laboratory, innoME is confident a new standard can be set in monitoring. If you'd like a closer look for yourself, be sure to attend the "Know your stuff 4.0" presentation at the Young and Innovative Companies Pavilion, where the developers from innoME and essentim will be demonstrating how you can harness this technology and the benefits it offers for your own applications.
innoME GmbH (32339 Espelkamp, Germany), Hall 20, Stand A12, (1),Topic: Young and Innovative Companies Pavilion
Contact: Regine Fuchs
Tel.: +49 57 72 91 14-0

Cell-ebrity Big Brother!
Anyone who has ever worked on cell cultures, whether intensively or even in passing, knows how it feels to wonder what’s going on behind that closed incubator door. What are the cells doing? Are they OK? Are they growing as well as expected, worse, or maybe even better?

The IncuCyte S3 live-cell analysis system can easily answer all these questions - and Essen Bioscience from the UK is revealing how at LABVOLUTION 2017 in Hannover. From the outside, the system looks no different from any run-of-the-mill mini cell incubator - but it's what's going on behind those closed doors that really counts. The IncuCyte S3 sits inside a standard incubator (a list of compatible equipment is available), and the cells can be added either in standard culture flasks or in microtiter plates (Essen Bioscience also cites vessels from numerous major producers) for continuous monitoring. The trick is that IncuCyte takes pictures or videos at intervals set by the user, which it then analyzes to check the cells' health and growth. It can also just as easily monitor complex processes - such as migration, invasion or killing - in situ, i.e. without the need to remove the cells from the incubator! This enables an entirely new kind of real-time analysis, which includes extended kinetic analysis, as the measurements can be continued for days or even weeks without having to set a - potentially inopportune - finishing point.

IncuCyte can hold up to six microplates at once, which makes it possible to conduct separate experiments in tandem. Multiplex measurements can also be taken in 96- or 384-well format. IncuCyte S3 can thus take a considerable part of the workload off users, who can simply sit back and relax once the measuring process has started, or rather attend to other pressing tasks. IncuCyte automatically performs the image-based data capture for the specified length of time. Further information is on offer on Tuesday, 16 May, between 10 and 11 a.m. in a presentation entitled "Enabling automated, real-time, analysis of cell health, proliferation, movement and function while cells remain unperturbed within your incubator" at the LabUSER Exhibitors' Forum in Hall 19. And if that's not enough, visitors to LABVOLUTION are warmly invited to take a close-up look at the device in action at the special induction session the company is offering at its stand on 17 May from 11.30 a.m. to 1.30 p.m.
Essen BioScience Ltd. (Welwyn Garden City AL7 3AX, UK), Hall 20, Stand D05
Contact: Yvonne Borsetti
Tel.: +49 208 8837 5904

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