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LABVOLUTION 2021, 04 - 06 May
LABVOLUTION News

LABVOLUTION TRENDSPOTS - No. 2

Does a small tube of blood hold the key to precision medicine?
Taiwanese start-up MiCareo is on a mission to decipher the information stored in cells as the gateway to precision medicine. The company has chosen LABVOLUTION 2019 in Hannover to unveil its MiSelect R System.

12 Apr. 2019

Does a small tube of blood hold the key to precision medicine?
Taiwanese start-up MiCareo is on a mission to decipher the information stored in cells as the gateway to precision medicine. The company has chosen LABVOLUTION 2019 in Hannover to unveil its MiSelect R System.

MiCareo is a venture capital-backed start-up based in the Neihu Technology Park in the Taiwanese capital city Taipei, where it occupies over 1,400 square meters of laboratory and office space, including a certified microfluidic chip manufacturing space (ISO class 4 in accordance with DIN EN ISO 14644-1). Its state-of-the-art facilities have attracted an impressive team of experts in microfluidics, optics, engineering, software, biology, clinical practice and regulatory approval. MiCareo believes the future lies in precision medicine - offering the right treatment for the right patient at the right time. In pursuit of this goal, MiCareo is intently focused on unlocking the crucial information hidden away deep inside the cells that circulate around our bodies.

The result of this ambitious endeavor is the MiSelect R System, which the company is now unveiling at LABVOLUTION 2019 in Hannover. MiCareo explains that from just one tube of blood, this device can isolate and profile a single live cell to extract biological and genomic information. The system is capable of characterizing up to 13 biomarkers for analysis with integrated staining and imaging, and also makes it possible to retrieve single cells for downstream analysis. The team will be delighted to explain more about the functions and provide further details at LABVOLUTION in Hannover.

MiCareo Taiwan Co., Ltd. (Taipei City 114, Taiwan), Hall 20, Stand D29/1
Contact: Lifan Wu
Tel: +886 2 2796 5096 502
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Helping everyone see the light - not just researchers!
BERTHOLD TECHNOLOGIES is back in Hannover for LABVOLUTION 2019, where it’s unveiling the new Sirius II LB 9526 tube luminometer, among other exciting innovations.

BERTHOLD TECHNOLOGIES GmbH & Co. KG is a privately run company that provides cutting-edge life science technology to customers around the world, both developing and producing its bioanalytical system solutions exclusively in Germany. Its comprehensive product portfolio includes small standalone readers (such as microvolume spectrometers and luminometers), various multimode microplate readers, microplate washers and microplate workstations, RIA and ELISA automation products, HPLC radio detectors and high-end imaging systems. BERTHOLD has its sights set on helping its customers significantly improve people’s quality of life with the aid of its user-friendly, high-precision bioanalytical solutions. At LABVOLUTION 2019 in Hannover, BERTHOLD is unveiling another device that goes toward making this mission a reality - the new Sirius II LB 9526 tube luminometer.

As the name suggests, luminometers are used to measure the luminescence of reagents. BERTHOLD TECHNOLOGIES was one of the early adopters of this measuring system, which was first introduced in the 1960s, and has developed and released more than twenty different types over the last four decades - covering everything from tubes to microplates. In fact, BERTHOLD TECHNOLOGIES remains the undisputed market leader in the field to this day. The new, supersensitive Sirius II LB 9526 tube luminometer sports a uniquely compact design, features a built-in touchscreen computer, and can be equipped with up to two injectors. Its light collection capabilities are maximized thanks to the detector’s proximity to the sample and optimized light reflectors surrounding it.

BERTHOLD TECHNOLOGIES GmbH & Co. KG (75323 Bad Wildbad, Germany), Hall 20, Stand A39
Contact: Andrea Gößner
Tel.: +49 7081 177-200
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Organs à la carte?
Turning the science fiction of synthetic organs into medical fact - that's the vision of CELLBRICKS. The startup is showcasing its innovative 3D bioprinting technology at the TU Berlin pavilion during LABVOLUTION 2019.

With some 33,500 students, around 100 different courses and 40 institutes, the Technische Universität Berlin is one of Germany's biggest, most prestigious and tradition-steeped universities. Its teaching and research efforts, high-caliber graduates and cutting-edge, service-oriented management have earned it an outstanding global reputation, right at the heart of Europe. The seven faculties cover a broad range of disciplines that provide a unique combination of natural sciences and technology with planning, business and social sciences, not to mention humanities. At this year’s LABVOLUTION, the TU Berlin is once again hosting a pavilion to showcase a series of projects proposing exciting, future-focused solutions – including bioprinting technology pioneered by the startup CELLBRICKS.

CELLBRICKS believes 3D bioprinting technology holds the key to solving a range of 21st-century medical challenges. For instance, 3D-printed cell structures simulating human tissue and organs could well overhaul established approaches to developing medicines. Not only might this put an end to testing on animals, but the customized, precision medicine it enables could revolutionize medical treatments. To pave the way for this major advance, CELLBRICKS is developing complex biological cell culture systems on a proprietary stereolithography-based bioprinting platform. The team predicts this will set entirely new standards in the quality, speed and accessibility of three-dimensional cell culture systems.

Technische Universität Berlin (10623 Berlin, Germany), Hall 20, Stand C70/1
Contact: Stefanie Terp
Tel.: +49 30 314-23922
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The Brits are blazing the trail - steering LIMS onto the data highway!
Laboratories are having to cope with expanding volumes of data at the same time as meeting increasingly strict standards. The new Matrix Gemini laboratory information management system (LIMS) from Autoscribe Informatics is specially designed to do both.

Laboratories around the world are undergoing the same transition as virtually all other spheres. Whether it's in industry, trade, not to mention our personal lives, more and more data is being collected everywhere, and this trend is set to grow exponentially. We somehow need to get a handle on this deluge of data - right across the board, but perhaps nowhere more acutely than in laboratories. That’s why Autoscribe Informatics (based just outside London) specializes in configurable, future-proof database management applications. The company’s leading solutions include laboratory information management systems (LIMS) that can be configured to suit customer requirements and easily tailored to meet specific needs. The company is attending LABVOLUTION 2019 to debut Matrix Gemini - its latest take on the optimum LIMS.

According to its developers, Matrix Gemini actually does what other suppliers so often promise. The system's exceptional configurability, user-friendly tools and resulting excellent functionality make it possible to implement a LIMS without having to make changes to the core code. This is said to simplify customer support, save time, reduce costs and maximize return on investment. Matrix is already being used in laboratories around the world and is suitable for a wide range of sectors. The dual desktop/web-based interface in Matrix Gemini now offers additional flexibility by allowing users to change workstations at will - from the lab, to the office, and even outdoors - as it's specially designed to run on virtually any mobile device.

Autoscribe Informatics Ltd. (RG7 8DA Reading, United Kingdom), Hall 19, Stand D77
Contact: Emely Haverich
Tel.: +44 118 9840 610
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Smartphones poised to hunt down spoiled meat?
A feasibility study conducted at Leibniz University Hannover has developed the first ever optical SPR sensors for smartphones that can be directly integrated into laboratory procedures - without any extra components.

The Hannover Center for Optical Technologies (HOT) at Leibniz University Hannover conducts interdisciplinary research and teaching in applied optics and photonics. At the initiative of a number of institutes and research centers at Hannover University and the Hannover Laser Center, HOT was created to pool individual specialisms in this field, open up new lines of research, and benefit research, teaching and the transfer of knowledge. At LABVOLUTION 2019, HOT is unveiling the optical SPR sensors it has developed for smartphones in a collaborative project with the Institute of Technical Chemistry (TCI).

Surface plasmon resonance (SPR) sensors are the current "gold standard" among marker-free optical biosensors, but till now they were firmly restricted to laboratory environments due to their size and expense. However, a feasibility study at Hannover University has produced the first ever optical SPR sensor, based on an optical glass fiber with a silver-coated glass-fiber core, that can be evaluated using a diffraction grating and the LED flashlight and camera of a smartphone. The first performance test has already demonstrated a sensitivity of 5.96 10-4 refractive index units (RIU)/pixel. Such straightforward measuring procedures raise the possibility of creating highly specific biosensors for use with ordinary smartphones that could be integrated into laboratory work both simply and cost-effectively - and without any additional equipment required. Not only that, but even non-technical staff could use these new smartphone biosensors as the basis for developing new products in tele-, travel and veterinary medicine or food analysis, to name just a few possibilities.

Gottfried Wilhelm Leibniz University Hannover – Hannover Center for Optical Technologies HOT (30167 Hannover, Germany), Hall 20, Stand D20
Contact: Mechtild Freiin von Münchhausen
Tel.: +49 511 762-5355
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Pure flexibility!
The InnuPure C16 touch from Analytik Jena combines high-precision liquid handling with automated extraction of high-quality nucleic acids. In addition to boosting efficiency, the device is also designed to set new standards in safety and user-friendly operation.

Part of the Swiss Endress+Hauser Group, Analytik Jena is a leading supplier of high-end analytical measuring technology, instruments and products used in the fields of biotechnology and molecular diagnostics as well as high-quality liquid handling and automation technology. Alongside traditional analysis techniques, especially for measuring concentrations of elements and molecules, the company offers end-to-end systems for bioanalytical life science applications that span a sample's highly complex analysis cycle - from preparation all the way through to detection. Also incorporating automated high-throughput pharmaceutical screening systems, the comprehensive portfolio is rounded off by a range of services plus instrument-specific consumables and disposable materials such as reagents and plastic products.

One of Analytik Jena's exhibits at this year's LABVOLUTION is the innovative InnuPure C16 touch, which combines high-precision liquid handling with automated extraction of high-quality nucleic acids. According to the manufacturer, this device can significantly boost the efficiency of nucleic acid extraction, whether magnetic particle separation or innovative SmartExtraction technology is used. The InnuPure C16 touch benefits from largely intuitive operation via a 10-inch tablet PC, with software that recommends customized optimizations based on the starting material. What’s more, the InnuPure C16 touch's high-precision pipetting system is designed to ensure accurate processes that can be reproduced whenever required. An integrated dosage unit enables elution volumes of 20 to 500 microliters to be set and then transferred automatically. The accompanying extraction kits are designed to reduce the risk of cross-contamination to an absolute minimum. Another advantage is a piercing tool that eliminates the need for manual removal of foils from the sealed reagent plastic. The mixing of buffer solutions and the resulting performance losses are also virtually eliminated according to Analytik Jena. Last but not least, an optional UV lamp can be integrated to prevent further sources of contamination.

Analytik Jena AG (07745 Jena, Germany), Hall 20, Stand B62
Contact: Dana Schmidt
Tel.: +49 3641 77-92 81
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For photos and video clips, visit: Trendspots / Product Innovations

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