LABVOLUTION Digital Edition |
With inserts, communication between different cell types can be analyzed by co-cultivation or studying the transcellular transport of substances. In addition, cell culture inserts can be used to investigate the reaction of cells to various substances, e.g. with chemotaxis, drug transport and migration assays. Last but not least, 3D epithelial models cultivated in cell culture inserts are used to estimate the corrosive or irritating properties of chemicals on human skin.
Earlier cell culture insert systems had several shortcomings. Prior to starting the test, users had to decide whether they wanted to utilize the cell culture inserts in Petri dishes or multiwell plates in a standing or hanging position. Both variants have their own advantages and disadvantages. If it became evident during initial tests that the other insert system would be more suitable, the entire setup would have to be changed, which is both time-consuming and costly. This meant changing the cultivation surfaces and thus an alteration of test parameters.
The BRAND® Insert 2in1 cell culture insert eliminates this system drawback. As the first insert that can be used in both a hanging and standing position without any additional accessories, it gives users complete flexibility. Equipped with a catch and three stands, the inserts fit exactly in 6-, 12-, and 24-well plates. This design consistently allows adequate room for a clean, low-contamination change of media. If the inserts are placed in a standing or hanging position, the stands and catch ensure that the membrane is placed securely over the bottom of the cell culture vessel with a parallel orientation.
Many cell lines thrive particularly well thanks to the cellGradeTM plus surface – without any additional coatings. Consistent cell growth ensures reproducible results for a wide variety of analyses.
Pipetting liquids without introducing foreign particles or microorganisms is a core task at many laboratories, for example when preparing samples, packaging media ...
Pipetting is often time-consuming in the laboratory both for routine tasks such as serial dilutions, as well as for more complex methods such as PCR.
Long pipetting series in the laboratory can lead to strain such as RSI (Repetitive Strain Injury). The manual microliter pipette Transferpette S by BRAND® protects ...