LABVOLUTION 2019, 21 - 23 May
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High-density cell culture bioreactor

Logo Dunn Labortechnik


Dunn Labortechnik

Exhibitor details
Exhibitor details
Logo High-density cell culture bioreactor

Product description

BelloCell is a disposable bioreactor from Cesco Bioengineering capable of high density cell culture for protein expression, virus and monoclonal antibody production and is available in Germany from Dunn Labortechnik.
BelloCells design is based on the concept of bellow-induced flow alternation of media and air through the porous matrices of BioNOC II microcarrier, where cells live and grow, providing a low shear, high aeration and foam free culture environment.
The BelloCell bioreactor consists of two components: a sterile, single-use culture BelloCell bottle and a bellow compressor BelloStage. When in use, the BelloCell bottle is partially filled with media and inoculated with cells.
The medium is raised and lowered alternatively to submerge and expose the cells growing on the BioNocII microcarrier, creating a dynamic interface between air and media on cell surfaces to maximize nutrient uptake and oxygen transfer.
One BelloCell bottle, with a specific surface area of 15.600 cm2, is capable of producing cell mass comparable to 20 to 30 roller bottles.
Since the matrix surface is specially treated, BelloCell can grow many anchorage-dependent cells and allows easy harvest of whole cells, cell components or secreted proteins.

Product website

Hall 20, Stand A59

(Main stand)

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