LABVOLUTION Digital Edition | September 2021
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Magnetic cell separation

Reversible reagents for receptor-and antigen specific cell isolation

Logo IBA Lifesciences


IBA Lifesciences

Exhibitor details
Exhibitor details
Logo Magnetic cell separation

Product description

MHC I Streptamers® and Fab Streptamers® for positive selection of T cells from PBMCs with magnetic microbeads. Low affinity Strep-tagged Fab fragments or MHC I molecules are multimerized with Strep-Tactin®, a streptavidin derivative, to generate multimers with high binding avidity. Strep-Tactin magnetic beads are used for magnetic cell isolation. Upon addition of low concentrations of biotin (Vitamin H), which competes with high affinity for the binding of Strep-tag to Strep-Tactin®, isolation reagents dissociate rapidly from the cell surface. This reversibility enables sequential positive cell selections with magnetic beads.

Product website

Hall 19, Stand B73

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