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HPE BlueTower System- enabeling high performance electrophoresis
The SERVA HPE BlueTower System is a multilevel flatbed electrophoresis device providing unmatched resolution, reproducibility and sensitivity - the first true »High Performance Electrophoresis (HPE)« system.
HPE BlueTower is a flatbed system for horizontal electrophoresis using precast gels, self-cast gels and gel strips. Main applications are isoelectric focusing (IEF) including the run of IPG strips (like SERVA IPG BlueStrips) in 2D PAGE and SDS PAGE, but also the separation of nucleic acids in polyacrylamide gels. In the field of biotechnology, this technique is applied for the separation of antibodies and antibody conjugates, but also for HCP 2D Western Blot analysis as an alternative to ELISA or MS analysis.
The system allows the simultaneous electrophoresis of several gels in 1D or 2D gel electrophoresis under high-precision temperature control. A cooling plate made of special ceramics, connected to an external cooling device, is responsible for the very precise temperature evenly distributed over the entire gel. Foil-supported gels in various formats have been developed especially for applications in 2D electrophoresis and isoelectric focusing. This coordinated system technology enables highest resolution and outstanding results, which is clearly superior to conventional vertical 2D electrophoresis and delivers up to 25% more spots compared to traditional vertical 2D PAGE (Moche et al., Electrophoresis 2013, 34, 1510-1516).
SERVA supplies the following film-backed precast gels for the HPE BlueTower system:
- HPE 2D gels for the 2nd dimension in 2D PAGE
- SERVA IPG BlueStrips for the 1st dimension in 2D PAGE
- SERVALYT PRECOTES/PreNets & FocusGel for IEF
- CleanGels for 1D PAGE.
The HPE Tower System is supplied with the following components: HPE BlueTower, power supply BP-3000-HPE and external cooling unit HPE-CU1.
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